Description
Parvexon® Plus – Features & Description
Active Ingredients & Formulation
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Parvaquone – 150 mg/mL (theilericidal agent targeting schizonts and piroplasms)
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Frusemide – 55 mg/mL (potent loop diuretic designed to relieve pulmonary edema)
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Ready-to-use, single injectable oil-based solution for intramuscular administration
Indications & Uses
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Primary Use: Treats East Coast Fever (Theileriosis) in cattle
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Special Role: Specifically formulated for advanced ECF with pulmonary edema, addressing both the parasitic infection and its respiratory complications
Key Benefits
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Dual-Action Formula:
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Parvaquone disrupts theilerial parasites in multiple stages
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Frusemide quickly reduces lung fluid accumulation, leading to faster recovery from respiratory distress
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Improved Cure Rates:
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Clinical trials in Tanzania showed an 89% cure rate in severe but uncomplicated cases with Parvaquone+Frusemide, compared to 40% using parvaquone alone
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Overall survival better than parvaquone alone (77% vs. 71%)
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Pulmonary Symptom Relief: Onset of improvement in 24–48 hours due to diuretic effect
Dosage & Administration
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Dose: 1 mL per 15 kg body weight (≈10 mg parvaquone + 3.6 mg frusemide per kg)
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Route: Intramuscular injection into neck muscles
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Repeat: After 48 hours; in severe cases with pulmonary edema, continue daily at half-dose intervals after initial treatment
Pack Sizes & Withdrawal
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Vials Available:
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50 mL (72 per case)
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100 mL (48 per case)
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Withdrawal Periods:
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Meat/offal: 28 days
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Milk: 14 days
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Features Summary Table
Feature | Description |
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Active Ingredients | Parvaquone 150 mg/mL + Frusemide 55 mg/mL |
Formulation | Oil-based injectable, IM administration |
Primary Use | Treat ECF, especially with pulmonary edema |
Dosage | 1 mL per 15 kg; repeat at 48 h; continue low-dose if needed for pulmonary signs |
Efficacy | 89% cure in severe but uncomplicated cases; faster resolution of respiratory distress |
Withdrawal | Meat/offal – 28 days; Milk – 14 days |
Pack Sizes | 50 mL and 100 mL vials |
Benefits | Treats both parasite and edema; high survival rates |
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