Parvexon Plus-Injection-100ml

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Description

Parvexon® Plus – Features & Description

Active Ingredients & Formulation

  • Parvaquone – 150 mg/mL (theilericidal agent targeting schizonts and piroplasms)

  • Frusemide – 55 mg/mL (potent loop diuretic designed to relieve pulmonary edema)

  • Ready-to-use, single injectable oil-based solution for intramuscular administration

Indications & Uses

  • Primary Use: Treats East Coast Fever (Theileriosis) in cattle

  • Special Role: Specifically formulated for advanced ECF with pulmonary edema, addressing both the parasitic infection and its respiratory complications

Key Benefits

  • Dual-Action Formula:

    • Parvaquone disrupts theilerial parasites in multiple stages

    • Frusemide quickly reduces lung fluid accumulation, leading to faster recovery from respiratory distress

  • Improved Cure Rates:

    • Clinical trials in Tanzania showed an 89% cure rate in severe but uncomplicated cases with Parvaquone+Frusemide, compared to 40% using parvaquone alone

    • Overall survival better than parvaquone alone (77% vs. 71%)

  • Pulmonary Symptom Relief: Onset of improvement in 24–48 hours due to diuretic effect

 Dosage & Administration

  • Dose: 1 mL per 15 kg body weight (≈10 mg parvaquone + 3.6 mg frusemide per kg)

  • Route: Intramuscular injection into neck muscles

  • Repeat: After 48 hours; in severe cases with pulmonary edema, continue daily at half-dose intervals after initial treatment

 Pack Sizes & Withdrawal

  • Vials Available:

    • 50 mL (72 per case)

    • 100 mL (48 per case)

  • Withdrawal Periods:

    • Meat/offal: 28 days

    • Milk: 14 days


Features Summary Table

Feature Description
Active Ingredients Parvaquone 150 mg/mL + Frusemide 55 mg/mL
Formulation Oil-based injectable, IM administration
Primary Use Treat ECF, especially with pulmonary edema
Dosage 1 mL per 15 kg; repeat at 48 h; continue low-dose if needed for pulmonary signs
Efficacy 89% cure in severe but uncomplicated cases; faster resolution of respiratory distress
Withdrawal Meat/offal – 28 days; Milk – 14 days
Pack Sizes 50 mL and 100 mL vials
Benefits Treats both parasite and edema; high survival rates

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